SCHEMBL2904115

SCHEMBL2904115

CNCCN.CO[Si](CCc1ccccc1)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL17417251 0.87 HTR2A (0.50) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2
SCHEMBL106416 0.83 TDP1 (0.46) TAAR1ATMCYP2A6HTR2ASMN1; SMN2
SCHEMBL17417253 0.81 SIGMAR1 (0.39) TAAR1SIGMAR1CYP2A6HTR2ASMN1; SMN2
SCHEMBL37761 0.80 SIGMAR1 (0.42) SIGMAR1GAA
SCHEMBL27424871 0.79 SIGMAR1 (0.38) TAAR1KMT2ASIGMAR1CYP2A6HTR2A
SCHEMBL447454 0.79 DRD2 (0.46) MEN1KMT2ASIGMAR1GAA
SCHEMBL8775075 0.78 SIGMAR1 (0.46) TAAR1MEN1KMT2ASIGMAR1SMN1; SMN2
SCHEMBL11252138 0.78 HTR2A (0.44) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2
SCHEMBL28175344 0.77 SIGMAR1 (0.44) SIGMAR1
SCHEMBL2488885 0.77 HTR2A (0.42) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014137195-A1 METHOD FOR PRODUCING NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE AND NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE PRODUCED THEREBY 광운대학교 산학협력단 (KR) 2014-09-12 WO claimed
EP-0346768-B1 Films primed with an aminofunctional silane, and film laminates thereof HOECHST CELANESE CORP (US) 1995-09-06 EP claimed
EP-2246039-B1 Method for dyeing hair comprising the step of treating the hair with an organic silicon compound ORÉAL L (FR) 2016-08-10 EP disclosed
EP-2213334-B1 Cosmetic composition comprising a specific alkoxysilane and an antibacterial gum; use of said composition for styling hair. ORÉAL L (FR) 2015-09-30 EP disclosed
EP-1767189-B1 Cosmetic composition comprising organic silicium compound and process for shaping hair OREAL (FR) 2014-03-05 EP disclosed
EP-2213334-A1 Cosmetic composition comprising a specific alkoxysilane and an antibacterial gum; use of said composition for styling hair. L'Oréal (FR) 2010-08-04 EP disclosed
EP-1767189-A2 Cosmetic composition comprising organic silicium compound and process for shaping hair L'OREAL (FR) 2007-03-28 EP disclosed
US-4826752-A Dry photosensitive lithographic plate comprising a silicon rubber layer containing an aromatic aminosilane FUJI PHOTO FILM CO., LTD. (JP) 1989-05-02 US disclosed