SCHEMBL29043223

SCHEMBL29043223

N#Cc1cc(C(=O)c2ccccc2)c(O)cc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.53
MEN1 O00255 5/20 0.53
GAA P10253 3/20 0.53
USP2 O75604 1/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
LMNA P02545 4/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CYP3A4 P08684 1/20 0.50
RECQL P46063 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CNR2 P34972 1/20 0.48
ALDH1A1 P00352 4/20 0.46
HTT P42858 3/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CYP2D6 P10635 1/20 0.46
SLC6A2 P23975 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30553037 1.00 KMT2A (0.53) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL295850 0.82 KMT2A (0.68) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL30063117 0.80 LMNA (0.66) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL170272 0.80 LMNA (0.66) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL7046942 0.80 KMT2A (0.70) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL11609471 0.79 MAPT (0.65) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL11120199 0.78 NPSR1 (0.47) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL1200740 0.77 AKR1C3 (0.55) GAALMNAMAPTCNR2ALDH1A1
SCHEMBL7066561 0.77 MEN1 (0.62) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL7328069 0.77 HNF4A (0.50) KMT2AMEN1GAAUSP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118024701-B Preparation method of sheet, scratch-resistant hot-bending sheet and application of sheet in clothing 汕头市亮彩新材料科技有限公司 2024-06-07 CN claimed
CN-118024701-A Preparation method of sheet, scratch-resistant hot-bending sheet and application of sheet in clothing 汕头市亮彩新材料科技有限公司 2024-05-14 CN claimed
CN-116278254-A Preparation method of moisture-absorbing sweat-releasing sun-screening fabric based on nylon filaments with special-shaped cross sections, fabric and application of fabric 汕头市兴裕泰纺织有限公司 2023-06-23 CN claimed
CN-118024701-B Preparation method of sheet, scratch-resistant hot-bending sheet and application of sheet in clothing 汕头市亮彩新材料科技有限公司 2024-06-07 CN disclosed
CN-118024701-A Preparation method of sheet, scratch-resistant hot-bending sheet and application of sheet in clothing 汕头市亮彩新材料科技有限公司 2024-05-14 CN disclosed
CN-116278254-A Preparation method of moisture-absorbing sweat-releasing sun-screening fabric based on nylon filaments with special-shaped cross sections, fabric and application of fabric 汕头市兴裕泰纺织有限公司 2023-06-23 CN disclosed