Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653282 | 0.79 | ALOX5 (0.33) | MAOBUSP2ALDH1A1MAPTMAPK1 | |
| SCHEMBL10653287 | 0.79 | ALOX5 (0.33) | MAOBUSP2ALDH1A1MAPTMAPK1 | |
| SCHEMBL16766999 | 0.78 | LMNA (0.36) | MAPTMAPK1 | |
| SCHEMBL25181319 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL7030925 | 0.76 | DRD1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL19757219 | 0.73 | MAOB (0.64) | MAOBASIC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3442252 | 0.72 | METAP2 (0.50) | ALDH1A1MAPT | |
| SCHEMBL1926319 | 0.72 | METAP2 (0.50) | ALDH1A1MAPT | |
| Cyanide SCHEMBL22130105 | 0.71 | LMNA (0.51) | MAOBASIC1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2671869 | 0.71 | METAP2 (0.48) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232070-B | Quinolinone alkaloid derivative containing acylhydrazone group on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-06-30 | — | — | CN | disclosed |