Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653287 | 1.00 | ALOX5 (0.33) | ALOX5NFKB1NFKB2RELAALOX12 | |
| SCHEMBL16766999 | 0.86 | LMNA (0.36) | CYP1A2MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL27607863 | 0.85 | ALDH1A1 (0.44) | ALOX5KDM4EMAPTALDH1A1MAPK1 | |
| SCHEMBL25181319 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1TP53KMT2A | |
| SCHEMBL7030925 | 0.83 | DRD1 (0.39) | KDM4EMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29044190 | 0.79 | MAOB (0.42) | MAPTALDH1A1MAPK1CA12CA1 | |
| SCHEMBL27698415 | 0.77 | CYP19A1 (0.39) | RELAKDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL16800868 | 0.76 | CYP1A2 (0.45) | NFKB1NFKB2RELAKDM4ECYP1A2 | |
| SCHEMBL1645103 | 0.76 | METAP2 (0.50) | MAPTNPC1RAB9ACA12MEN1 | |
| SCHEMBL1260621 | 0.76 | LMNA (0.32) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| US-4539161-A | OPTICAL BRIGHTNERS, FLUORESCENT DYES | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |