Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3003250 | 0.89 | L3MBTL1 (0.61) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL4018265 | 0.84 | L3MBTL1 (0.60) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL13997174 | 0.83 | L3MBTL1 (0.53) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL13207381 | 0.81 | ALDH1A1 (0.74) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL13242909 | 0.78 | SMN1; SMN2 (0.43) | L3MBTL1PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3594763 | 0.78 | ALDH1A1 (1.00) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL8630241 | 0.77 | L3MBTL1 (1.00) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10517128 | 0.76 | ALDH1A1 (0.97) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL9370578 | 0.75 | ALDH1A1 (0.78) | L3MBTL1PKMALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL2902134 | 0.74 | SMN1; SMN2 (0.50) | L3MBTL1ALDH1A1CYP2C9SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160391-B1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2167467-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-03-31 | — | — | EP | disclosed |
| EP-2160391-A1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | Bayer CropScience AG (DE) | 2010-03-10 | — | — | EP | disclosed |
| EP-2014658-A1 | Nicotinamide derivatives and method for their manufacture | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2014658-A1 | Nicotinamide derivatives and method for their manufacture | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2009001-A1 | Method for manufacturing dioxazine derivatives | Bayer CropScience AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-2009001-A1 | Method for manufacturing dioxazine derivatives | Bayer CropScience AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2008155004-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155004-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155003-A1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | NAMPT, NQO1, NNT | L3MBTL1 4513/4885PKM 1452/4885ALDH1A1 139/4885 |
| US-20100184973-A1 | Method for producing dioxazine derivatives | CYP4Z1, CYP1A1, CYP2F1 | L3MBTL1 4848/4885PKM 1784/4885ALDH1A1 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.