Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904881 | 0.93 | RAB9A (0.39) | ALDH1A1KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL2907498 | 0.93 | RAB9A (0.38) | ALDH1A1POLBRECQLKDM4EMAPT | |
| SCHEMBL2903975 | 0.90 | POLB (0.39) | ALDH1A1POLBRECQLKDM4EMAPK1 | |
| SCHEMBL2913211 | 0.90 | POLB (0.46) | ALDH1A1POLBRECQLKDM4EMAPK1 | |
| SCHEMBL2910394 | 0.88 | KDM4E (0.39) | ALDH1A1POLBKDM4EMAPTMAPK1 | |
| SCHEMBL2910392 | 0.88 | ALDH1A1 (0.35) | ALDH1A1POLBRECQLMAPK1HTT | |
| SCHEMBL2912942 | 0.88 | ALDH1A1 (0.35) | ALDH1A1POLBRECQLMAPK1HTT | |
| SCHEMBL2910867 | 0.87 | ALDH1A1 (0.33) | ALDH1A1POLBRECQLMAPK1HTT | |
| SCHEMBL2909834 | 0.87 | ALDH1A1 (0.33) | ALDH1A1POLBRECQLMAPK1HTT | |
| SCHEMBL2908076 | 0.85 | GSK3B (0.44) | ALDH1A1POLBRECQLPARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |