Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PTGFR | P43088 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67323 | 0.79 | MTNR1A (0.44) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1555330 | 0.77 | ALDH1A1 (0.50) | CYP3A4CYP2C9KMT2AMEN1CYP2C19 | |
| SCHEMBL23636332 | 0.76 | TP53 (0.48) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9995385 | 0.76 | CYP3A4 (0.35) | CRHBPCRHR2CYP3A4CYP2C9KMT2A | |
| SCHEMBL17728900 | 0.76 | HTR3E (0.44) | KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1026693 | 0.76 | ALDH1A1 (0.42) | PTGS1CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL7379122 | 0.76 | RXRA (0.45) | AKR1C3CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL1025144 | 0.76 | SCN2A (0.39) | CRHBPCRHR2CYP3A4CYP2C9KMT2A | |
| SCHEMBL7034982 | 0.75 | KMT2A (0.47) | CYP3A4CYP2C9KMT2AMEN1CYP2C19 | |
| SCHEMBL688212 | 0.73 | CES2 (0.38) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454186-B | Aryl formanilide compound containing pentafluorothio and preparation method and application thereof | 山东省联合农药工业有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-111454202-B | Heteroaryl formanilide compound containing pentafluorothio and preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-10-01 | — | — | CN | disclosed |