Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989015 | 0.97 | BLM (0.32) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| SCHEMBL28217967 | 0.94 | BLM (0.31) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Sulfuric Acid SCHEMBL6263301 | 0.77 | TSHR (0.42) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| SCHEMBL23199767 | 0.74 | CA1 (0.32) | BLMALOX15CA1LMNAPMP22 | |
| SCHEMBL18498735 | 0.72 | BLM (0.31) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| Pivalamide SCHEMBL7280681 | 0.71 | CA2 (0.35) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| SCHEMBL1169404 | 0.71 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL866857 | 0.71 | ALDH1A1 (0.46) | CYP2D6CYP2C19ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL27768757 | 0.69 | TSHR (0.40) | BLMKDM4ECYP2D6CYP2C19NPSR1 | |
| SCHEMBL8574238 | 0.69 | CA2 (0.33) | BLMKDM4ECYP2D6CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490489-A | Method for producing Methacrylic Acid (MAS) and/or alkyl methacrylate optimized by reducing interfering byproducts | 罗姆化学有限责任公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116490488-A | Method for preparing alkyl methacrylate optimized by reducing interfering byproducts | 罗姆化学有限责任公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116348444-A | Improved process for the preparation of methyl methacrylate and/or methacrylic acid with reduced back mixing during conversion | 罗姆化学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |