Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768757 | 0.91 | TSHR (0.40) | TSHRALDH1A1BLMKDM4ECYP2D6 | |
| SCHEMBL28263163 | 0.87 | ALDH1A1 (0.53) | TSHRALDH1A1BLMLMNAALOX15 | |
| SCHEMBL322454 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL27534940 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5007373 | 0.83 | — | — | |
| Methyl Alcohol SCHEMBL11101619 | 0.83 | — | — | |
| Benzene SCHEMBL28151441 | 0.78 | TSHR (0.53) | TSHRALDH1A1BLMCYP2C19LMNA | |
| SCHEMBL6834582 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1BLMLMNAALOX15 | |
| Sulfuric Acid SCHEMBL29045867 | 0.77 | BLM (0.36) | TSHRALDH1A1BLMKDM4ECYP2D6 | |
| Sulfuric Acid SCHEMBL2127329 | 0.76 | CA5A (0.46) | TSHRALDH1A1BLMKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010604-A1 | OPTIMIZED PROCESS FOR SYNTHESIZING METHACRYLIC ACID (MAA) AND/OR ALKYL METHACRYLATE BY REDUCING UNWANTED BYPRODUCTS | RÖHM GMBH (DE) | 2024-01-11 | — | — | US | disclosed |
| US-20230416184-A1 | OPTIMIZED PROCESS FOR SYNTHESIZING ALKYL METHACRYLATE BY REDUCING UNWANTED BYPRODUCTS | RÖHM GMBH (DE) | 2023-12-28 | — | — | US | disclosed |
| US-20230399286-A1 | IMPROVED PROCESS FOR PREPARING METHYL METHACRYLATE AND/OR METHACRYLIC ACID BY REDUCED BACK MIXING DURING CONVERSION | RÖHM GMBH (DE) | 2023-12-14 | — | — | US | disclosed |
| CN-116490489-A | Method for producing Methacrylic Acid (MAS) and/or alkyl methacrylate optimized by reducing interfering byproducts | 罗姆化学有限责任公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116490488-A | Method for preparing alkyl methacrylate optimized by reducing interfering byproducts | 罗姆化学有限责任公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116348444-A | Improved process for the preparation of methyl methacrylate and/or methacrylic acid with reduced back mixing during conversion | 罗姆化学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-106244654-A | A kind of enzyme transforming process prepares the method for L alanyl L alanine | 精晶药业股份有限公司 | 2016-12-21 | — | — | CN | disclosed |
| EP-1275636-B1 | Process for preparing methacrylamide sulfate | ARKEMA (FR) | 2005-11-02 | — | — | EP | disclosed |
| CN-1220675-C | Process and appts. for prepn. of sulfurized methylacryloyl amine | ATOFINAS S A (FR) | 2005-09-28 | — | — | CN | disclosed |
| US-6750368-B2 | FROM ACETONE CYANOHYDRIN, SULPHURIC ACID AND SULFUR TRIOXIDE IN A MULTISTEP PROCESS | ATOFINA (FR) | 2004-06-15 | — | — | US | disclosed |
| US-20030088123-A1 | Process for preparing sulphuric methacrylamide and device for implementing it | TRINSEO EUROPE GMBH (CH) | 2003-05-08 | — | — | US | disclosed |
| CN-1397546-A | Process and appts. for prepn. of sulfurized methylacryloyl amine | ATOFINAS S A (FR) | 2003-02-19 | — | — | CN | disclosed |
| EP-1275636-A1 | Process for preparing methacrylamide sulfate and device to carry out the process | Atofina (FR) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010604-A1 | OPTIMIZED PROCESS FOR SYNTHESIZING METHACRYLIC ACID (MAA) AND/OR ALKYL METHACRYLATE BY REDUCING UNWANTED BYPRODUCTS | MMAB, NAAA, ACMSD | TSHR 4042/4885ALDH1A1 134/4885BLM 486/4885 |
| US-20230416184-A1 | OPTIMIZED PROCESS FOR SYNTHESIZING ALKYL METHACRYLATE BY REDUCING UNWANTED BYPRODUCTS | MMAB, ACMSD, AS3MT | TSHR 4409/4885ALDH1A1 416/4885BLM 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.