Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047573 | 0.82 | CA1 (0.40) | LMNAALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL29047632 | 0.82 | ERN1 (0.47) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29047606 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL29047611 | 0.77 | TDP1 (0.49) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29047698 | 0.77 | LMNA (0.43) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11745047 | 0.76 | ALDH1A1 (0.50) | LMNAALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL29047625 | 0.75 | ALDH1A1 (0.44) | PTGES2KAT6ALMNAALDH1A1MEN1 | |
| SCHEMBL29047589 | 0.73 | ERN1 (0.47) | LMNAALDH1A1MEN1KMT2AADORA2A | |
| SCHEMBL28328818 | 0.71 | LMNA (0.56) | CHRM5PTGES2LMNAALDH1A1KMT2A | |
| SCHEMBL27619654 | 0.71 | TDP1 (0.61) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |