Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047698 | 0.84 | LMNA (0.43) | ALDH1A1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL29047615 | 0.82 | SLC22A12 (0.39) | ALDH1A1LMNATDP1MEN1KMT2A | |
| SCHEMBL16495095 | 0.81 | GAA (0.51) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL29047611 | 0.81 | TDP1 (0.49) | ERN1ALDH1A1LMNANFE2L2TDP1 | |
| SCHEMBL29047606 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNANFE2L2TDP1PPARG | |
| SCHEMBL11745047 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TRIM24TRIM33LMNANFE2L2 | |
| SCHEMBL29047573 | 0.77 | CA1 (0.40) | ALDH1A1LMNANFE2L2HTTSMN1; SMN2 | |
| SCHEMBL8384637 | 0.76 | ERN1 (0.59) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL2795501 | 0.76 | ERN1 (0.54) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL29047589 | 0.76 | ERN1 (0.47) | ERN1ALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |