Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047698 | 0.82 | LMNA (0.43) | TDP1PPARGALDH1A1MAPTLMNA | |
| SCHEMBL29047606 | 0.82 | ALDH1A1 (0.43) | TDP1ITGA1PPARGALDH1A1LMNA | |
| SCHEMBL28234782 | 0.81 | TDP1 (0.54) | TDP1ITGA1PPARGALDH1A1MAPT | |
| SCHEMBL29047632 | 0.81 | ERN1 (0.47) | TDP1ERN1PPARGALDH1A1MAPT | |
| SCHEMBL11745047 | 0.80 | ALDH1A1 (0.50) | TDP1PPARGALDH1A1LMNAGAA | |
| SCHEMBL29047573 | 0.78 | CA1 (0.40) | TDP1PPARGALDH1A1MAPTLMNA | |
| SCHEMBL9486445 | 0.78 | TDP1 (0.51) | TDP1ITGA1PPARGALDH1A1MAPT | |
| SCHEMBL29047589 | 0.77 | ERN1 (0.47) | ERN1ALDH1A1MAPTLMNACA1 | |
| SCHEMBL29047615 | 0.77 | SLC22A12 (0.39) | TDP1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9950317 | 0.75 | ITGA1 (0.55) | TDP1ITGA1PPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |