SCHEMBL290477

SCHEMBL290477

O=C1Oc2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.54
TSHR P16473 1/20 0.54
STK17B O94768 6/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 1/20 0.50
MCL1 Q07820 1/20 0.50
CDC25B P30305 1/20 0.48
MAOA P21397 3/20 0.47
HDAC3 O15379 3/20 0.47
HDAC4 P56524 3/20 0.47
HDAC1 Q13547 3/20 0.47
HDAC7 Q8WUI4 3/20 0.47
HDAC2 Q92769 3/20 0.47
HDAC10 Q969S8 3/20 0.47
HDAC11 Q96DB2 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707476 1.00 PKM (0.54) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL8466712 0.92 PKM (0.52) PKMTSHRSTK17BMEN1KMT2A
Dimethyl Sulfoxide SCHEMBL29085605 0.87 STK17B (0.44) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL167093 0.83
SCHEMBL12691224 0.83 TDP1 (0.63) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL19754922 0.83 TDP1 (0.63) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL30320031 0.83 TDP1 (0.63) PKMTSHRSTK17BMEN1KMT2A
Acrylic Acid SCHEMBL31497014 0.82 STK17B (0.49) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL13397579 0.81 STK17B (0.47) PKMTSHRSTK17BMEN1KMT2A
SCHEMBL3261837 0.80 STK17B (0.50) PKMTSHRSTK17BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137268-A Carboxymethyl cellulose-ionic liquid-conductive polymer film and preparation method and application thereof 南京理工大学 2025-06-13 CN claimed
CN-119230299-A Solid-state capacitor and preparation method thereof 聚镕光电(广州)新材料科技有限公司 2024-12-31 CN claimed
EP-3303312-B1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL)(2-HYDROXYPHENYL)METHANONE O-METHYL OXIME ARYSTA LIFESCIENCE CORP (JP) 2023-07-19 EP claimed
US-20220154222-A1 NOVEL NUCLEIC ACID MODIFIERS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2022-05-19 US claimed
CN-109153773-B Ladder-type polybenzobifurans 国际商业机器公司 2021-02-26 CN claimed
WO-2020186213-A1 NOVEL NUCLEIC ACID MODIFIERS THE BROAD INSTITUTE, INC. (US) 2020-09-17 WO claimed
EP-3699178-A1 PROCESS FOR PREPARING FLUOXASTROBIN Arysta LifeScience Corporation (JP) 2020-08-26 EP claimed
EP-3019495-B1 PROCESS FOR PREPARING FLUOXASTROBIN ARYSTA LIFESCIENCE CORP (JP) 2020-06-03 EP claimed
CN-109689060-A combination chemotherapy 系统肿瘤学有限公司 2019-04-26 CN claimed
US-10087152-B2 Process for preparing (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyl oxime ARYSTA LIFESCIENCE CORPORATION (JP) 2018-10-02 US claimed
US-6479675-B1 Processes for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines BAYER AKTIENGESELLSCHAFT (DE) 2002-11-12 US claimed
US-6472498-B2 COLORLESS UBE INDUSTRIES, LTD. (JP) 2002-10-29 US claimed
CN-1343207-A Benzofuran-2-ones as colorants for organic materials CIBA SC HOLDING AG (CH) 2002-04-03 CN claimed
US-20020019512-A1 Diaryl carbonate product and production of polycarbonate UBE INDUSTRIES, LTD. 2002-02-14 US claimed
EP-1178033-A1 Process for the purification of diaryl carbonate and process for the production of polycarbonate Ube Industries, Ltd. (JP) 2002-02-06 EP claimed
EP-1159276-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS Ciba SC Holding AG (CH) 2001-12-05 EP claimed
US-6150521-A Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines BAYER AKTIENGESELLSCHAFT (DE) 2000-11-21 US claimed
WO-2000053597-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-14 WO claimed
EP-0670841-B1 AMORPHOUS SOLID MODIFICATION OF 2,2',2''-NITRILO TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE] CIBA GEIGY AG (CH) 1997-01-22 EP claimed
US-4385006-A Process for preparing aromatic nitriles 501 SOCIETE FRANCAISE HOECHST (FR) 1983-05-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019512-A1 Diaryl carbonate product and production of polycarbonate PKD1, APC, PKD2 PKM 2826/4885TSHR 4819/4885STK17B 3574/4885
US-10087152-B2 Process for preparing (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyl oxime HMOX2, HAO2, HMOX1 PKM 1721/4885TSHR 3439/4885STK17B 2311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.