Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546967 | 1.00 | ALOX15 (0.46) | ALOX15LMNAMAPK14RXFP1GRM4 | |
| SCHEMBL29047655 | 0.91 | MAPK14 (0.48) | LMNAMAPK14RXFP1NR3C1PDE4B | |
| SCHEMBL30546971 | 0.91 | MAPK14 (0.48) | LMNAMAPK14RXFP1NR3C1PDE4B | |
| SCHEMBL29047677 | 0.90 | LMNA (0.47) | LMNARXFP1MAPK3MAPK1MRGPRX1 | |
| SCHEMBL30546930 | 0.90 | LMNA (0.47) | LMNARXFP1MAPK3MAPK1MRGPRX1 | |
| SCHEMBL29047661 | 0.89 | MAPK1 (0.42) | LMNAMAPK14RXFP1MAPK3MAPK1 | |
| SCHEMBL30546942 | 0.89 | MAPK1 (0.42) | LMNAMAPK14RXFP1MAPK3MAPK1 | |
| SCHEMBL29047709 | 0.88 | TAS2R14 (0.47) | LMNAMAPK14RXFP1MAPK3MAPK1 | |
| SCHEMBL30546928 | 0.88 | TAS2R14 (0.47) | LMNAMAPK14RXFP1MAPK3MAPK1 | |
| SCHEMBL30546976 | 0.85 | LMNA (0.49) | LMNAMAPK14RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |