Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494523 | 0.87 | LIPE (0.37) | ELOVL1DPP4MMP13 | |
| SCHEMBL24253841 | 0.87 | LIPE (0.37) | ELOVL1DPP4MMP13 | |
| SCHEMBL24253624 | 0.84 | ELOVL1 (0.37) | ELOVL1HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL30423985 | 0.82 | HCRTR1 (0.35) | CYP11B2HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL24253866 | 0.82 | HCRTR1 (0.35) | CYP11B2HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL24253950 | 0.81 | GPR119 (0.36) | ELOVL1 | |
| SCHEMBL30423581 | 0.80 | ELOVL1 (0.35) | ELOVL1HCRTR1HCRTR2KCNH2LTC4S | |
| SCHEMBL24253859 | 0.80 | ELOVL1 (0.35) | ELOVL1HCRTR1HCRTR2KCNH2LTC4S | |
| SCHEMBL24253644 | 0.79 | ELOVL1 (0.41) | ELOVL1HTR1ADRD2ADRA1DADRA1A | |
| SCHEMBL30424148 | 0.79 | ELOVL1 (0.41) | ELOVL1HTR1ADRD2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | disclosed |