Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MPI | P34949 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906516 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17802261 | 0.86 | ALDH1A1 (0.61) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL19361114 | 0.86 | LMNA (0.58) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL3676964 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17808869 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17802270 | 0.85 | LMNA (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL2905604 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL2901489 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17808863 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL13833755 | 0.83 | PKM (0.58) | KDM4EALDH1A1GAALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2215910-A1 | QUORUM SENSING INHIBITOR | The University of Tokyo (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2215910-A1 | QUORUM SENSING INHIBITOR | The University of Tokyo (JP) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | BLVRB, API5, Q6ZSR9 | KDM4E 497/4885ALDH1A1 2904/4885GAA 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.