Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MPI | P34949 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676964 | 0.92 | ALDH1A1 (0.58) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL2905604 | 0.91 | KDM4E (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL2905445 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL19361114 | 0.86 | LMNA (0.58) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL11805447 | 0.84 | PKM (0.56) | KDM4EALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL17802261 | 0.84 | ALDH1A1 (0.61) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17808813 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17802270 | 0.82 | LMNA (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL17808869 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL2901489 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1GAALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022897-A | 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2215910-A1 | QUORUM SENSING INHIBITOR | The University of Tokyo (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2215910-A1 | QUORUM SENSING INHIBITOR | The University of Tokyo (JP) | 2010-08-11 | — | — | EP | disclosed |
| US-4022897-A | 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | BLVRB, API5, Q6ZSR9 | KDM4E 497/4885ALDH1A1 2904/4885GAA 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.