Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026093 | 0.79 | HTT (0.66) | ALDH1A1HTTSIGMAR1DRD4DRD3 | |
| SCHEMBL12420819 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1LMNACYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL2197173 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SIGMAR1LMNACYP3A4CYP2C9 | |
| SCHEMBL32667767 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SIGMAR1ADORA2ALMNAMEN1 | |
| SCHEMBL32667704 | 0.75 | SIGMAR1 (0.56) | LTA4HSIGMAR1MEN1CYP2C19BLM | |
| SCHEMBL30790557 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HTTSIGMAR1LMNAMEN1 | |
| SCHEMBL32667411 | 0.73 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1MEN1BLMKMT2A | |
| SCHEMBL29060004 | 0.72 | LTA4H (0.53) | ALDH1A1LTA4HDPP4LMNAMEN1 | |
| SCHEMBL21823759 | 0.71 | LTA4H (0.71) | ALDH1A1LTA4HDPP4HTTLMNA | |
| SCHEMBL32667410 | 0.71 | DRD2 (0.55) | SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028326-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | GLUETACS THERAPEUTICS SHANGHAI CO LTD (CN) | 2026-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028326-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | CDR2, CYC1, CLN6 | ALDH1A1 527/4885LTA4H 2170/4885DPP4 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.