SCHEMBL29060741

SCHEMBL29060741

CCCCC(O)CCS(=O)(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.48
MMP13 P45452 4/20 0.47
MMP1 P03956 3/20 0.46
MMP7 P09237 3/20 0.46
MMP12 P39900 3/20 0.46
ACE P12821 2/20 0.46
HSD11B1 P28845 3/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29060735 0.94 FFAR4 (0.46) PSIP1MMP13MMP1MMP7MMP12
SCHEMBL7207708 0.82 MMP13 (0.71) MMP13MMP1HTT
SCHEMBL27496051 0.81 PSIP1 (0.48) PSIP1MMP13MMP1MMP7MMP12
SCHEMBL777886 0.79 PSIP1 (0.64) PSIP1MMP13MMP1HSD11B1TDP1
SCHEMBL10539070 0.78 HSD11B1 (0.54) PSIP1MMP13MMP1MMP7MMP12
SCHEMBL28763540 0.78 PSIP1 (0.52) PSIP1MMP13MMP1HSD11B1ALDH1A1
Benzene SCHEMBL6390523 0.77 PSIP1 (0.61) PSIP1MMP13MMP1HSD11B1TDP1
SCHEMBL2445501 0.77 PSIP1 (0.61) PSIP1MMP13MMP1HSD11B1TDP1
SCHEMBL3193732 0.77 MMP12 (0.49) PSIP1MMP13MMP7MMP12HSD11B1
SCHEMBL6673936 0.75 PSIP1 (0.59) PSIP1MMP13MMP1HSD11B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606232-A Novel monofluoroalkyl compounds, preparation method and application thereof 许昌学院 2023-08-18 CN disclosed