SCHEMBL28763540

SCHEMBL28763540

CC(O)CCS(=O)(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.52
HSD11B1 P28845 7/20 0.49
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
POLB P06746 1/20 0.44
MMP1 P03956 1/20 0.44
MMP13 P45452 1/20 0.44
KMT2A Q03164 1/20 0.43
MMP2 P08253 1/20 0.43
MMP3 P08254 1/20 0.43
MMP9 P14780 1/20 0.43
MMP14 P50281 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7924711 0.85 MMP2 (0.63) ALDH1A1HTTPOLBMMP1MMP13
SCHEMBL2448610 0.84 PSIP1 (0.56) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL8474920 0.83 ALDH1A1 (0.60) ALDH1A1MAPTMMP1MMP13KMT2A
SCHEMBL27279139 0.81 HSD11B1 (0.50) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL7000851 0.81 PSIP1 (0.48) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL28973785 0.81 PSIP1 (0.52) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL20996662 0.81 MMP13 (0.65) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL28973817 0.81 PSIP1 (0.52) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL20087726 0.80 HSD11B1 (0.49) PSIP1HSD11B1ALDH1A1TP53HTT
SCHEMBL7724605 0.80 PSIP1 (0.56) PSIP1HSD11B1ALDH1A1TP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716296-B Efficient halogenation synthesis method of alkyl halide 润药仁智(北京)科技有限公司 2023-12-12 CN disclosed
CN-116606232-A Novel monofluoroalkyl compounds, preparation method and application thereof 许昌学院 2023-08-18 CN disclosed
CN-114716296-A Efficient halogenation synthesis method of alkyl halide 北京大学 2022-07-08 CN disclosed
CN-114634432-A High-efficiency synthesis method of alkyl aryl thioether compound 北京大学 2022-06-17 CN disclosed