Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890414 | 0.79 | MCL1 (0.43) | MCL1 | |
| SCHEMBL11854167 | 0.78 | ADRA2A (0.35) | — | |
| SCHEMBL21891774 | 0.78 | — | — | |
| SCHEMBL2728485 | 0.76 | NAAA (0.45) | — | |
| SCHEMBL28699927 | 0.76 | DGKA (0.41) | — | |
| SCHEMBL23231149 | 0.74 | MCL1 (0.40) | MCL1 | |
| SCHEMBL111548 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL20368988 | 0.74 | NAAA (0.41) | MCL1 | |
| SCHEMBL11662224 | 0.74 | — | — | |
| SCHEMBL23130194 | 0.73 | DGKA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217557-B1 | ACTIVATED METHYLENE REAGENTS | Henkel IP & Holding GmbH (DE) | 2018-01-24 | — | — | EP | disclosed |
| EP-2217557-B1 | ACTIVATED METHYLENE REAGENTS | Henkel IP & Holding GmbH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-20140155556-A1 | ADHESIVE SYSTEMS USING IMINES AND SALTS THEREOF, PRECURSORS TO ELECTRON DEFICIENT OLEFINS AND COREACTANTS THEREFOR | Henkel IP & Holding GmbH (DE) | 2014-06-05 | — | — | US | disclosed |
| US-20140018487-A1 | Adhesive Systems Using Imines and Salts Thereof, Precursors to Electron Deficient Olefins and Coreactants Therefor | LOCTITE (R&D) LIMITED (IE) | 2014-01-16 | — | — | US | disclosed |
| US-8481755-B2 | Activated methylene reagents and curable compositions prepared therefrom | HENKEL IRELAND LTD. (DE) | 2013-07-09 | — | — | US | disclosed |
| US-8481755-B2 | Activated methylene reagents and curable compositions prepared therefrom | HENKEL IRELAND LTD. (DE) | 2013-07-09 | — | — | US | disclosed |
| EP-2217557-A2 | ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM | Loctite (R & D) Limited (IE) | 2010-08-18 | — | — | EP | disclosed |
| US-20100199888-A1 | ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM | LOCTITE (R&D) LIMITED (IE) | 2010-08-12 | — | — | US | disclosed |
| US-20100199888-A1 | ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM | LOCTITE (R&D) LIMITED (IE) | 2010-08-12 | — | — | US | disclosed |
| WO-2009053482-A2 | ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM | LOCTITE (R & D) LIMITED (IE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053483-A1 | ADHESIVE SYSTEMS USING IMINES AND SALTS THEREOF, PRECURSORS TO ELECTRON DEFICIENT OLEFINS AND COREACTANTS THEREFOR | LOCTITE (R & D) LIMITED (IE) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100199888-A1 | ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM | NOTUM, WASF2, BHMT2 | MCL1 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.