Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
| ▸ | SYK | P43405 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909451 | 0.81 | SYK (0.38) | SYKCYP3A4CYP2C19GRM4 | |
| SCHEMBL5655346 | 0.70 | IRAK4 (0.36) | — | |
| SCHEMBL2909504 | 0.69 | SYK (0.41) | SYK | |
| SCHEMBL2908516 | 0.68 | CHRNB2 (0.40) | SYK | |
| SCHEMBL2910038 | 0.66 | SYK (0.39) | SYKGRM4 | |
| SCHEMBL2905403 | 0.64 | PDE4D (0.44) | — | |
| SCHEMBL2903176 | 0.64 | PDE4D (0.44) | — | |
| SCHEMBL2901842 | 0.62 | PDE4D (0.38) | SYK | |
| SCHEMBL30450714 | 0.61 | GRM4 (0.43) | CCNT1GRM4 | |
| SCHEMBL4136062 | 0.61 | PDE4D (0.37) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-B1 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARM CORP (US) | 2010-08-18 | — | — | EP | claimed |