Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820907 | 0.83 | MTNR1B (0.43) | RAB9ANPC1SLC2A1AKT1AKT2 | |
| SCHEMBL22615062 | 0.77 | RAB9A (0.70) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2906472 | 0.74 | GABRA1 (0.42) | RAB9ANPC1SLC2A1AKT1AKT2 | |
| SCHEMBL2899627 | 0.72 | ALDH1A3 (0.70) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19951014 | 0.69 | PKM (0.38) | RAB9ANPC1SLC2A1AKT1AKT2 | |
| SCHEMBL29833387 | 0.68 | TRIM33 (0.53) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21566092 | 0.67 | CYP11B1 (0.47) | RAB9ANPC1SLC2A1AKT1AKT2 | |
| SCHEMBL21852751 | 0.67 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTAPP | |
| SCHEMBL2623445 | 0.67 | ESR2 (0.58) | RAB9ANPC1SMN1; SMN2APP | |
| SCHEMBL19175444 | 0.67 | CLK4 (0.53) | RAB9ANPC1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216052-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |