Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013595 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8555900 | 0.76 | CA12 (0.50) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4624469 | 0.72 | CES1 (0.73) | ALDH1A1ALDH2ALDH3A1CES1BCHE | |
| SCHEMBL909935 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ETSHRHSD17B10 | |
| SCHEMBL30634566 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ETSHRHSD17B10 | |
| SCHEMBL5710968 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ETSHRHSD17B10 | |
| SCHEMBL6013602 | 0.71 | TTR (0.47) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL9034857 | 0.71 | AADAT (0.36) | ALDH1A1KDM4EALDH2ALDH3A1CES1 | |
| SCHEMBL526807 | 0.69 | KDM4E (0.68) | ALDH1A1HTTKDM4ETSHRMEN1 | |
| SCHEMBL29459619 | 0.69 | KDM4E (0.68) | ALDH1A1HTTKDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |