SCHEMBL2906590

SCHEMBL2906590

Cc1cc(Oc2ccc(-c3ccc(O)cc3)cc2)nc(Oc2ccc(-c3ccc(O)cc3)cc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
GAA P10253 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPK1 P28482 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
HPGD P15428 2/20 0.45
ATM Q13315 1/20 0.45
TSHR P16473 5/20 0.45
LMNA P02545 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
NPC1 O15118 2/20 0.45
HTT P42858 3/20 0.44
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906444 0.95 ALDH1A1 (0.58) ALDH1A1GAASMN1; SMN2POLBMAPT
SCHEMBL2898204 0.84 ALDH1A1 (0.51) ALDH1A1GAASMN1; SMN2POLBMAPT
SCHEMBL2901468 0.83 ESR2 (0.45) ALDH1A1GAASMN1; SMN2MAPTL3MBTL1
SCHEMBL2906573 0.80 HPGD (0.49) ALDH1A1GAASMN1; SMN2MAPTL3MBTL1
SCHEMBL7902841 0.79 ALDH1A1 (0.55) ALDH1A1GAASMN1; SMN2POLBMAPT
SCHEMBL5634255 0.77 MEN1 (0.50) ALDH1A1GAASMN1; SMN2MAPTL3MBTL1
SCHEMBL2898805 0.76 ALDH1A1 (0.45) ALDH1A1GAASMN1; SMN2MAPTL3MBTL1
SCHEMBL2905883 0.74 HPGD (0.53) ALDH1A1GAASMN1; SMN2MAPTL3MBTL1
SCHEMBL2906037 0.74 MAPT (0.42) GAAMAPTL3MBTL1MEN1KMT2A
SCHEMBL8864396 0.73 MEN1 (0.65) ALDH1A1MAPTL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed
EP-1636209-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT Sumitomo Chemical Company, Limited (JP) 2006-03-22 EP disclosed
WO-2004113327-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-29 WO disclosed