Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459746 | 0.84 | EPHX2 (0.42) | SMN1; SMN2ALDH1A1EPHX2TSHRRAB9A | |
| SCHEMBL18120313 | 0.81 | MEN1 (0.44) | SMN1; SMN2ALDH1A1EPHX2TSHRRAB9A | |
| SCHEMBL3553857 | 0.78 | TRPA1 (0.54) | SMN1; SMN2ALDH1A1TRPA1MAPTGAA | |
| SCHEMBL1577787 | 0.77 | MEN1 (0.41) | SMN1; SMN2TSHRHPGD | |
| SCHEMBL1577477 | 0.77 | MEN1 (0.41) | SMN1; SMN2TSHRHPGD | |
| SCHEMBL4818015 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TRPA1EPHX2TSHRMAPT | |
| SCHEMBL15849987 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1EPHX2TSHRFAAH | |
| SCHEMBL11120633 | 0.73 | FAAH (0.42) | SMN1; SMN2ALDH1A1TRPA1TSHRFAAH | |
| SCHEMBL444178 | 0.73 | DGKA (0.48) | ALDH1A1TSHRMAPT | |
| SCHEMBL14978924 | 0.73 | MEN1 (0.39) | SMN1; SMN2ALDH1A1TRPA1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116712561-A | Antibody-drug conjugates containing an N-methyleneamide linker | 杭州爱科瑞思生物医药有限公司 | 2023-09-08 | — | — | CN | disclosed |