SCHEMBL29067294

SCHEMBL29067294

CC(C)(C)OC(=O)N(c1cncs1)N1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.37
HPGD P15428 1/20 0.32
WNT1 P04628 1/20 0.31
GSK3B P49841 1/20 0.31
DYRK1A Q13627 1/20 0.31
BCL2 P10415 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9933946 0.75 PAX8 (0.38) GPR119
SCHEMBL28702674 0.72 GPR119 (0.43) GPR119WNT1GSK3BDYRK1ABCL2
SCHEMBL29067317 0.70 GPR119 (0.36) GPR119WNT1GSK3BDYRK1A
SCHEMBL6420418 0.70 MAPT (0.37) GPR119WNT1GSK3BDYRK1A
SCHEMBL4832991 0.69 GSTO1 (0.34) GPR119
SCHEMBL27877048 0.67 ELANE (0.37) GPR119
SCHEMBL4832540 0.67 NFKB1 (0.36) GPR119
SCHEMBL4820347 0.66 HPGD (0.39) HPGD
SCHEMBL27664908 0.65 HPGD (0.38) HPGD
SCHEMBL27836672 0.65 HPGD (0.38) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116507607-A Compounds and compositions as modulators of TLR signaling 神经孔疗法股份有限公司 2023-07-28 CN disclosed