SCHEMBL29067340

SCHEMBL29067340

O=Cc1ccc2c(c1)NC=CC=C2

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
KDM4E B2RXH2 1/20 0.34
PTGS2 P35354 1/20 0.34
RAB9A P51151 1/20 0.34
CYP2A6 P11509 4/20 0.33
AOX1 Q06278 1/20 0.33
KIF11 P52732 2/20 0.32
ALDH5A1 P51649 1/20 0.32
ABAT P80404 1/20 0.32
VCAM1 P19320 1/20 0.32
TSHR P16473 1/20 0.32
UNG P13051 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27471075 0.87 KDM4E (0.39) ALDH1A1KDM4EPTGS2RAB9ACYP2A6
SCHEMBL27476532 0.74 ALDH1A1 (0.33) ALDH1A1KDM4EPTGS2RAB9ACYP2A6
SCHEMBL2915154 0.72 DYRK1A (0.32) ALDH1A1KDM4E
SCHEMBL1247719 0.68 GAA (0.43) ALDH1A1KDM4ECYP2A6TSHRHSD17B10
SCHEMBL6648586 0.68 TNKS2 (0.39) ALDH1A1KDM4EPTGS2RAB9ACYP2A6
SCHEMBL34259 0.66 GAA (0.48)
Formic Acid Methyl Ester SCHEMBL17215301 0.66 MAPT (0.35) RAB9A
SCHEMBL8886564 0.65 ALDH1A1 (0.46) ALDH1A1KDM4EPTGS2RAB9ACYP2A6
SCHEMBL9160695 0.65 NAMPT (0.39) ALDH1A1KDM4ERAB9A
Bromide SCHEMBL10654286 0.65 GAA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116725967-A Valicarb isopropyl compound and process for producing the same 帕尔制药公司 2023-09-12 CN disclosed