Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067340 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL1247719 | 0.72 | GAA (0.43) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL25343552 | 0.72 | — | — | |
| SCHEMBL23166092 | 0.71 | KDM4E (0.34) | DYRK1AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL34259 | 0.70 | GAA (0.48) | MAPTGAA | |
| Iodide SCHEMBL12466756 | 0.68 | GAA (0.46) | MAPTGAA | |
| Hydrochloric Acid SCHEMBL160640 | 0.68 | GAA (0.46) | MAPTGAA | |
| SCHEMBL8654087 | 0.68 | GAA (0.46) | MAPTGAA | |
| Bromide SCHEMBL10654286 | 0.68 | GAA (0.46) | MAPTGAA | |
| SCHEMBL1787947 | 0.68 | GAA (0.46) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153400-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1985-09-04 | — | — | EP | claimed |
| EP-0135767-A1 | Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions | SCHERING CORPORATION (US) | 1985-04-03 | — | — | EP | claimed |
| WO-1985000808-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORP. (US) | 1985-02-28 | — | — | WO | claimed |
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-0153400-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1985-09-04 | — | — | EP | disclosed |
| EP-0135767-A1 | Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions | SCHERING CORPORATION (US) | 1985-04-03 | — | — | EP | disclosed |
| WO-1985000808-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORP. (US) | 1985-02-28 | — | — | WO | disclosed |