Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067517 | 0.84 | KMT2A (0.44) | SMN1; SMN2KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL29067527 | 0.79 | NPC1 (0.38) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL29067530 | 0.78 | KMT2A (0.38) | RAB9ANPC1KMT2AMAPTALDH1A1 | |
| SCHEMBL29067537 | 0.71 | MAPT (0.41) | RAB9ANPC1KMT2AMAPTHPGD | |
| SCHEMBL29714905 | 0.71 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL29067507 | 0.67 | ACP1 (0.32) | — | |
| SCHEMBL29067511 | 0.67 | TGM2 (0.42) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL29004445 | 0.67 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL1465687 | 0.66 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL29072372 | 0.66 | KMT2A (0.48) | RAB9ASMN1; SMN2NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |