Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067509 | 0.84 | RAB9A (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29067527 | 0.81 | NPC1 (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29067537 | 0.80 | MAPT (0.41) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL10050770 | 0.70 | MEN1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10037099 | 0.69 | RAPGEF4 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11351786 | 0.68 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11681121 | 0.67 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10394834 | 0.67 | RAPGEF4 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9973798 | 0.67 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8661773 | 0.67 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |