Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989014 | 0.81 | LMNA (0.50) | DRD2DRD4DRD3NOTUMPKM | |
| SCHEMBL20764923 | 0.81 | NOTUM (0.45) | NOTUMHRH3PKMKDM4EALDH1A1 | |
| SCHEMBL13723894 | 0.77 | NOTUM (0.47) | NOTUMHRH3KDM4EALDH1A1MAPK1 | |
| SCHEMBL15056311 | 0.74 | KAT6A (0.45) | DRD2DRD4DRD3NOTUMLMNA | |
| SCHEMBL30500456 | 0.74 | CHRNB2 (0.46) | PKMKDM4EALDH1A1MAPK1FFAR1 | |
| SCHEMBL29068037 | 0.74 | CHRNB2 (0.46) | PKMKDM4EALDH1A1MAPK1FFAR1 | |
| SCHEMBL5759590 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL12989738 | 0.71 | LMNA (0.50) | ALKBH1LMNANPC1GLARAB9A | |
| SCHEMBL28289846 | 0.71 | PKM (0.40) | PKMLMNAFFAR1GABRPGABRD | |
| SCHEMBL31310179 | 0.71 | NOTUM (0.46) | NOTUMPKMLMNAFFAR1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |