Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068037 | 0.77 | CHRNB2 (0.46) | PKMFFAR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL30500456 | 0.77 | CHRNB2 (0.46) | PKMFFAR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL27649564 | 0.75 | GRM5 (0.55) | PKMMAPK14GRM5 | |
| SCHEMBL3114626 | 0.73 | CHRNB2 (0.56) | CHRNB2CHRNA4LTA4H | |
| SCHEMBL27261493 | 0.73 | HRH4 (0.55) | PKM | |
| SCHEMBL29068134 | 0.71 | DRD2 (0.42) | PKMFFAR1GABRPGABRDGABRA1 | |
| SCHEMBL19263959 | 0.71 | LRRK2 (0.49) | FFAR1GABRA5CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL3104137 | 0.70 | GPR119 (0.55) | FFAR1CHRNB2CHRNA7CHRNA4GRM5 | |
| SCHEMBL1007069 | 0.70 | MAPT (0.39) | CHRNB2CHRNA7CHRNA4LMNAHTT | |
| SCHEMBL30454012 | 0.70 | CYP1A2 (0.55) | PKMFFAR1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689652-A | Fused heterocycle derivative, preparation method and its application medically | 北京诺诚健华医药科技有限公司 | 2019-04-26 | — | — | CN | disclosed |