Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774359 | 0.82 | CLK4 (0.45) | CLK4ADRA2CMAOBBRD4IDO1 | |
| SCHEMBL28589926 | 0.81 | ADRA2C (0.47) | CLK4ADRA2CMAOBIDO1NOTUM | |
| SCHEMBL1982974 | 0.80 | ADRA2C (0.50) | CLK4ADRA2CPGRBRD4LRRK2 | |
| SCHEMBL5634702 | 0.80 | ACHE (0.39) | CLK4MAOBIDO1LRRK2MAP4K4 | |
| SCHEMBL4506629 | 0.80 | ADRA2C (0.55) | CLK4ADRA2CMAOBPGRAR | |
| SCHEMBL14850862 | 0.77 | CLK4 (0.46) | CLK4ADRA2CMAOBPGRAR | |
| SCHEMBL2012945 | 0.77 | ACHE (0.39) | CLK4PGRMAP4K4 | |
| SCHEMBL7873514 | 0.77 | ESR2 (0.45) | — | |
| SCHEMBL4649579 | 0.75 | CLK4 (0.41) | CLK4ADRA2CMAOBPGRAR | |
| SCHEMBL695298 | 0.75 | ESR2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |