SCHEMBL5634702

SCHEMBL5634702

Cc1cccc(-c2cc[c]cc2C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
NISCH Q9Y2I1 2/20 0.38
MAOB P27338 1/20 0.37
ADORA1 P30542 2/20 0.37
ADORA2A P29274 1/20 0.37
RAB9A P51151 3/20 0.37
CNR2 P34972 2/20 0.36
LRRK2 Q5S007 2/20 0.36
CNR1 P21554 1/20 0.36
CHEK1 O14757 1/20 0.36
MAP4K4 O95819 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
CSF1R P07333 1/20 0.36
MET P08581 1/20 0.36
PDGFRB P09619 1/20 0.36
PIM1 P11309 1/20 0.36
FGFR1 P11362 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873514 0.82 ESR2 (0.45) KCNA3
SCHEMBL16720374 0.82 CNR2 (0.51) ACHECNR2CNR1
SCHEMBL2012945 0.82 ACHE (0.39) ACHENISCHRAB9AMAP4K4PIM1
SCHEMBL1045097 0.82 AKR1C3 (0.44) ACHEMAOBADORA1ADORA2ARAB9A
SCHEMBL695298 0.80 ESR2 (0.44) ACHERAB9ANPC1HPGDTSHR
SCHEMBL8093287 0.80 CYP1A1 (0.44) ACHEMAOBRAB9ACNR2NPC1
SCHEMBL3536486 0.80 CYP1A1 (0.44) ACHENISCHMAOBADORA1ADORA2A
SCHEMBL29068276 0.80 CLK4 (0.44) MAOBLRRK2MAP4K4CLK4IDO1
SCHEMBL695042 0.78 RAPGEF4 (0.41) ADORA1ADORA2AHPGDSMN1; SMN2IDO1
SCHEMBL1804627 0.78 AKR1C3 (0.36) ACHEMAOBADORA1ADORA2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118251380-A Spiro- (indan-fluorene) compounds and their use in organic electronic devices 多蒂肯独家合成控股公司 2024-06-25 CN disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
EP-4342883-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT Tosoh Corporation (JP) 2024-03-27 EP disclosed
CN-117440940-A Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element 东曹株式会社 2024-01-23 CN disclosed
CN-110997648-B Condensed ring compound 东曹株式会社 2023-12-19 CN disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-3621946-B1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-09-06 EP disclosed
CN-110740986-B Indane derivatives and their use in organic electronic devices 多蒂肯独家合成控股公司 2023-08-25 CN disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-116157382-A Material for metal patterning, amine compound, electronic device, and method for forming metal pattern 东曹株式会社 2023-05-23 CN disclosed
EP-3401305-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2018-11-14 EP disclosed
US-9698352-B2 Amine compound and use thereof TOSOH CORPORATION (JP) 2017-07-04 US disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
EP-2902391-B1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2017-03-08 EP disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2015-08-27 US disclosed
EP-2902391-A1 NOVEL AMINE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2015-08-05 EP disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
US-20070213374-A1 Malonamide Derivatives MERCK PATENT GMBH (DE) 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF DRD1, MLLT1, DRD4 ACHE 3088/4885NISCH 2891/4885MAOB 1439/4885
US-20070213374-A1 Malonamide Derivatives RAF1, BRAF, ARAF ACHE 4071/4885NISCH 2412/4885MAOB 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.