SCHEMBL29068307

SCHEMBL29068307

CCCCc1c(Br)c(Br)c(C)c(Br)c1Br

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SKP2 Q13309 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
TYMP P19971 1/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10012939 0.80 LMNA (0.31) LMNA
SCHEMBL9440814 0.79 TSHR (0.42) TYMPKDM4ELMNATSHR
SCHEMBL5588339 0.77 HPGD (0.45) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL5095924 0.76 ALDH1A1 (0.32) HPGDKDM4E
SCHEMBL5109742 0.75 GABRA1 (0.32) LMNA
SCHEMBL5587083 0.73 HPGD (0.42) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9485666 0.73 NPC1 (0.33) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL10831875 0.73 THRB (0.36) TYMPKDM4ELMNATSHR
SCHEMBL4633204 0.73 NPC1 (0.48) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL5589392 0.72 HPGD (0.41) HTTNPC1HPGDMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554635-A Flame-retardant ABS material and preparation method thereof 江苏松上科技有限公司 2023-08-08 CN claimed
CN-116554635-A Flame-retardant ABS material and preparation method thereof 江苏松上科技有限公司 2023-08-08 CN disclosed
CN-116554635-A Flame-retardant ABS material and preparation method thereof 江苏松上科技有限公司 2023-08-08 CN disclosed