Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25379641 | 0.82 | MAPT (0.64) | ALDH1A1MAPTEGFRNPSR1 | |
| SCHEMBL28391873 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2D6ATMMAPTMPO | |
| SCHEMBL4864671 | 0.75 | APP (0.70) | APPALDH1A1CYP2D6MAPTNCF1 | |
| SCHEMBL28323063 | 0.75 | ACP1 (0.44) | APPNCF1HTR6 | |
| SCHEMBL3391705 | 0.74 | APP (0.61) | APPALDH1A1CYP2D6ATMNCF1 | |
| SCHEMBL23175129 | 0.73 | LMNA (0.70) | ALDH1A1CYP2D6ATMMAPTPOLB | |
| SCHEMBL31410965 | 0.72 | APP (0.60) | APPMAPTNCF1 | |
| SCHEMBL34461806 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CYP2D6ATMMAPTPOLB | |
| SCHEMBL7172603 | 0.71 | APP (0.51) | APPMAPTNCF1PRUNE1EGFR | |
| SCHEMBL3953843 | 0.71 | APP (0.51) | APPMAPTNCF1PRUNE1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693458-A | Cycloalkyl or heterocyclyl substituted heteroaryl compounds, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2023-09-05 | — | — | CN | disclosed |