Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907288 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL6585676 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL7164543 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL6276955 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL234997 | 0.79 | MGAM (0.46) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL8217960 | 0.79 | MGAM (0.46) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL11285667 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL328925 | 0.79 | — | — | |
| SCHEMBL27828 | 0.78 | — | — | |
| SCHEMBL27845082 | 0.78 | MGAM (0.55) | ALDH1A1TRPA1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2916832-B1 | A PROCESS FOR THE PREPARATION OF PREGABALIN | HIKAL LTD (IN) | 2019-01-16 | — | — | EP | disclosed |
| US-10023885-B2 | Process for the preparation of pregabalin | HIKAL LIMITED (IN) | 2018-07-17 | — | — | US | disclosed |
| US-20150344919-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | HIKAL LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| US-20150344919-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | HIKAL LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| US-20100324139-A1 | PROCESS TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2010-12-23 | — | — | US | disclosed |
| US-20100324139-A1 | PROCESS TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2010-12-23 | — | — | US | disclosed |
| US-20100324139-A1 | PROCESS TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2010-12-23 | — | — | US | disclosed |
| EP-2222630-A1 | PROCESSES TO PREGABALIN | Generics (UK) Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009081208-A1 | PROCESSES TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081208-A1 | PROCESSES TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023885-B2 | Process for the preparation of pregabalin | CHRNA6, CHRNA9, ADH5 | ALDH1A1 214/4885TRPA1 1714/4885MGAM 357/4885 |
| US-20100324139-A1 | PROCESS TO PREGABALIN | GABRB2, GABRE, GABRB1 | ALDH1A1 921/4885TRPA1 1249/4885MGAM 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.