Sugi Predict

Sugi Predict / Compounds / SCHEMBL118817

SCHEMBL118817

SCHEMBL118817

O=C(O)c1ccnc(F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 10/20 0.61
▸ KDM5C P41229 7/20 0.61
▸ KDM5B Q9UGL1 6/20 0.61
▸ KDM2A Q9Y2K7 5/20 0.61
▸ KDM3A Q9Y4C1 5/20 0.61
▸ KDM4A O75164 5/20 0.61
▸ KDM4E B2RXH2 4/20 0.61
▸ KDM6B O15054 4/20 0.61
▸ KDM5A P29375 4/20 0.61
▸ KDM4D Q6B0I6 2/20 0.61
▸ TET3 O43151 1/20 0.61
▸ BBOX1 O75936 1/20 0.61
▸ ALDH1A1 P00352 1/20 0.61
▸ MAPT P10636 1/20 0.61
▸ ASPH Q12797 1/20 0.61
▸ TET2 Q6N021 1/20 0.61
▸ ALKBH5 Q6P6C2 1/20 0.61
▸ KDM7A Q6ZMT4 1/20 0.61
▸ KDM8 Q8N371 1/20 0.61
▸ TET1 Q8NFU7 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957382 1.00 KDM4C (0.61) KDM4CKDM5CKDM5BKDM2AKDM3A
Hydrochloric Acid SCHEMBL28045024 0.98 KDM4C (0.59) KDM4CKDM5CKDM5BKDM2AKDM3A
Nitrous Acid SCHEMBL29072872 0.92 KDM4C (0.53) KDM4CKDM5CKDM5BKDM2AKDM3A
Methacrylic Acid SCHEMBL11898560 0.88 KDM4C (0.49) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL29967026 0.81 TAS1R3 (0.48) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL2996754 0.81 PARP1 (0.48) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL3569008 0.81 TAS1R3 (0.44) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL1437180 0.81 TAS1R3 (0.48) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL29407015 0.77 KDM4C (0.78) KDM4CKDM5CKDM5BKDM2AKDM3A
SCHEMBL70700 0.77 KDM4C (0.78) KDM4CKDM5CKDM5BKDM2AKDM3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279730-B 2, 5-Or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group, useful as medicaments OM药物公司 2025-02-14 — — CN claimed
CN-118930884-A Fluorine-containing metal organic framework material for methane and nitrogen separation, and preparation method and application thereof 浙江工业大学 2024-11-12 — — CN claimed
CN-118007162-A Preparation method of carbon dioxide electro-reduction catalyst 中汽研汽车检验中心（天津）有限公司 2024-05-10 — — CN claimed
CN-117983310-A Carbon dioxide electro-reduction catalyst and preparation method thereof 中汽研汽车检验中心（天津）有限公司 2024-05-07 — — CN claimed
CN-116854720-A Isonicacid chelated aluminum oxide cluster compound, and macro preparation method and application thereof 闽都创新实验室 2023-10-10 — — CN claimed
CN-109212051-B Gas chromatography-mass spectrometry combined method for determining nine trace amounts of halogenated nicotinic acid in drinking water 丁立平 2021-11-19 — — CN claimed
CN-110818629-A Method for synthesizing fluoroisonicotinic acid derivative 杭州勇诚睿生物科技有限公司 2020-02-21 — — CN claimed
CN-109212051-A The gas chromatography-mass spectrometry of nine kinds of halogenated niacin of trace in a kind of measurement drinking water 丁立平 2019-01-15 — — CN claimed
WO-2011110488-A1 A NOVEL PET IMAGING AGENT OF AMYLOID PLAQUES AND ITS PRECURSOR BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-09-15 — — WO claimed
CN-101343366-A Nano-laminal compound with regular array of pyridine and its derivant, and preparation thereof UNIV SHANGHAI (CN) 2009-01-14 — — CN claimed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 — — US disclosed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 — — EP disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 — — EP disclosed
EP-4041732-B1 ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR ZHEJIANG METON PHARMACEUTICAL CO LTD (CN) 2026-03-18 — — EP disclosed
US-20260022108-A1 ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF TENARX, INC. 2026-01-22 — — US disclosed
WO-1991000093-A1 BIS-ACYLOXYMETHYL DERIVATIVES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1991-01-10 — — WO disclosed
US-4389403-A HYPOTENSIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1983-06-21 — — US disclosed
US-4046768-A 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 — — US disclosed
US-4045446-A 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-30 — — US disclosed
US-4033753-A HERICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors USP30, USP1, USP10 KDM4C 440/4885KDM5C 237/4885KDM5B 759/4885
US-20260022108-A1 ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF WNT1, WNT3, WNT3A KDM4C 1693/4885KDM5C 2599/4885KDM5B 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.