Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073342 | 0.83 | TRPA1 (0.39) | SLC6A2ROCK2PDE4BTRPV1ALDH1A1 | |
| SCHEMBL29073451 | 0.83 | SLC6A2 (0.52) | SLC6A2AADAT | |
| SCHEMBL5362433 | 0.80 | TBXAS1 (0.33) | ALDH1A1AADAT | |
| SCHEMBL29073370 | 0.79 | SLC6A2 (0.38) | SLC6A2AADATFPR1FPR2 | |
| SCHEMBL29073325 | 0.79 | SLC6A2 (0.38) | SLC6A2TRPV1AADATRPS6KB1TRPM8 | |
| SCHEMBL25331737 | 0.78 | PDE4B (0.40) | SLC6A2PDE4BTRPV1ALDH1A1HTT | |
| SCHEMBL27057694 | 0.76 | SLC6A2 (0.39) | SLC6A2PDE4BTRPV1FPR1FPR2 | |
| SCHEMBL30767936 | 0.76 | SLC6A2 (0.39) | SLC6A2PDE4BTRPV1FPR1FPR2 | |
| SCHEMBL29073363 | 0.75 | AADAT (0.41) | SLC6A2AADAT | |
| SCHEMBL31596872 | 0.73 | ROCK2 (0.42) | ROCK2PDE4BTRPV1TRPA1SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783165-A | 1,2,3, 4-tetrahydroquinoline derivatives as YAP/TAZ-TEAD activation inhibitors for the treatment of cancer | 天主教鲁汶大学 | 2023-09-19 | — | — | CN | disclosed |