Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551647 | 0.86 | SIGMAR1 (0.64) | ACHEDRD2DRD4DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8555397 | 0.84 | SIGMAR1 (0.62) | ACHEDRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL8315434 | 0.82 | ACHE (0.71) | ACHEDRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL21460095 | 0.81 | CTSL (0.46) | DRD2DRD3SIGMAR1HRH3TMEM97 | |
| SCHEMBL20178567 | 0.81 | CTSL (0.51) | SIGMAR1HRH3TMEM97CARM1PRMT6 | |
| SCHEMBL12482253 | 0.81 | CTSL (0.51) | SIGMAR1HRH3TMEM97CARM1PRMT6 | |
| SCHEMBL24652674 | 0.80 | NPC1 (0.58) | ACHEDRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL20594278 | 0.79 | SIGMAR1 (0.53) | DRD2DRD4DRD3SIGMAR1NPC1 | |
| SCHEMBL21920972 | 0.79 | SIGMAR1 (0.53) | DRD2DRD4DRD3SIGMAR1NPC1 | |
| SCHEMBL7299780 | 0.78 | CARM1 (0.60) | ACHESIGMAR1HRH3TMEM97CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648248-A | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |