Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.64 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8555397 | 0.98 | SIGMAR1 (0.62) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL7299780 | 0.91 | CARM1 (0.60) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL23972327 | 0.91 | LMNA (0.64) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL24652674 | 0.90 | NPC1 (0.58) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL29079552 | 0.86 | ACHE (0.51) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL23972324 | 0.85 | CARM1 (0.67) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL11403585 | 0.83 | ACHE (0.56) | SIGMAR1HRH3ACHEDRD2DRD4 | |
| SCHEMBL8646865 | 0.83 | CARM1 (0.64) | SIGMAR1CARM1PRMT6HRH3TMEM97 | |
| SCHEMBL11009529 | 0.82 | BCHE (0.65) | SIGMAR1ACHEDRD2DRD4BCHE | |
| SCHEMBL11226960 | 0.82 | CTSL (0.60) | SIGMAR1CARM1PRMT6HRH3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044216-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | Seqirus UK Limited (GB) | 2017-02-16 | — | — | US | disclosed |
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| CN-1183768-A | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 1998-06-03 | — | — | CN | disclosed |
| US-5753679-A | SCIZOPHRENIA | HOFFMANN-LA ROCHE INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044216-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION | MRPL21, CHLSN, MAX | SIGMAR1 4122/4885CARM1 3992/4885PRMT6 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.