SCHEMBL29080987

SCHEMBL29080987

O=P(F)(F)c1ccc(F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CA12 O43570 1/20 0.37
MMP2 P08253 1/20 0.37
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ACHE P22303 1/20 0.36
HPGD P15428 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BCL2L1 Q07817 1/20 0.32
BAD Q92934 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28666853 0.82 ACHE (0.43) CES2CES1CA12MMP2CA1
SCHEMBL9927352 0.79 CES2 (0.39) CES2CES1CA12MMP2CA1
SCHEMBL779999 0.79 CES2 (0.39) CES2CES1CA12MMP2CA1
SCHEMBL28431617 0.77 CES2 (0.38) CES2CES1CA12MMP2CA1
SCHEMBL781909 0.74 ACHE (0.41) CES2CES1CA12MMP2CA1
Hydrogen Peroxide SCHEMBL8672187 0.74 BCL2L1 (0.46) CES2CES1CA12MMP2CA1
SCHEMBL2540983 0.74 HPGD (0.59) CES2CES1CA12MMP2CA1
SCHEMBL1567573 0.74 CA2 (0.55) CES2CES1CA12MMP2CA1
SCHEMBL7775596 0.74 LMNA (0.56) CES2CES1CA12MMP2CA1
SCHEMBL11991140 0.74 BCL2L1 (0.46) CES2CES1CA12MMP2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN disclosed