Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567573 | 0.83 | CA2 (0.55) | LMNATSHRCA12MMP2CES2 | |
| SCHEMBL12606481 | 0.79 | MMP2 (0.42) | LMNATSHRCA12MMP2CES2 | |
| Hydrogen Peroxide SCHEMBL8672187 | 0.78 | BCL2L1 (0.46) | LMNACA12MMP2CES2CES1 | |
| Hydrogen Peroxide SCHEMBL8672190 | 0.78 | BCL2L1 (0.46) | LMNACA12MMP2CES2CES1 | |
| SCHEMBL9927352 | 0.77 | CES2 (0.39) | LMNACA12MMP2CES2CES1 | |
| SCHEMBL779999 | 0.77 | CES2 (0.39) | LMNACA12MMP2CES2CES1 | |
| SCHEMBL780122 | 0.74 | LMNA (0.34) | LMNATSHRCA12MMP2CA2 | |
| SCHEMBL916043 | 0.74 | LMNA (0.59) | LMNATSHRCA12MMP2CA2 | |
| SCHEMBL28431617 | 0.74 | CES2 (0.38) | CA12MMP2CES2CES1CA2 | |
| SCHEMBL28666853 | 0.74 | ACHE (0.43) | LMNATSHRCA12MMP2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | claimed |
| CN-109369716-B | Aryl phosphine oxide compound and synthesis method and application thereof | 广东工业大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-109096334-B | Preparation method of chiral aryl phosphine oxide compound and derivative thereof | 广西大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109369716-A | A kind of aryl oxidized phosphine compound and its synthetic method and application | 广东工业大学 | 2019-02-22 | — | — | CN | disclosed |