Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1188911 | 0.90 | CTSL (0.56) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL8913074 | 0.84 | CTSL (0.69) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL20582129 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL764273 | 0.78 | CTSL (0.64) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL19174541 | 0.75 | CTSL (0.62) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL26296178 | 0.75 | CTSL (0.62) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL3991791 | 0.75 | ALDH1A1 (0.46) | CTSLCTSBCTSSALDH1A1MAPK1 | |
| SCHEMBL19031238 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7657377 | 0.75 | CTSL (0.61) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL2746329 | 0.74 | RORC (0.43) | ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |