SCHEMBL8805010

SCHEMBL8805010

CC(=O)OC1CCCC(=O)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 2/20 0.35
CHRM2 P08172 4/20 0.34
CHRM4 P08173 4/20 0.34
CHRM1 P11229 4/20 0.34
CHRM3 P20309 4/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
POLB P06746 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP17A1 P05093 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19996621 1.00 THRB (0.45) THRBCYP3A4CYP2C9CYP2C19TDP1
SCHEMBL5985695 0.88 TDP1 (0.40) THRBCYP3A4CYP2C9CYP2C19TDP1
SCHEMBL11547378 0.88 TDP1 (0.40) THRBCYP3A4CYP2C9CYP2C19TDP1
SCHEMBL455306 0.82 THRB (0.41) THRBCYP3A4CYP2C9CYP2C19TDP1
SCHEMBL9687419 0.81 TRIM24 (0.42) CYP2C19PDE4APDE4BPDE4CPDE4D
SCHEMBL9957309 0.81 THRB (0.41) THRBCYP3A4CYP2C9CYP2C19MAPT
SCHEMBL29090337 0.81 THRB (0.41) THRBCYP3A4CYP2C9CYP2C19MAPT
SCHEMBL1795613 0.79
Methacrylic Acid SCHEMBL28177773 0.79 THRB (0.38) THRBCYP3A4CYP2C9CYP2C19
SCHEMBL450583 0.77 THRB (0.38) THRBCYP3A4CYP2C9CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581577-B1 15-OXOSTEROID COMPOUND AND METHOD FOR PRODUCING SAME ASKA PHARM CO LTD (JP) 2023-10-11 EP disclosed
WO-2023173417-A1 QUANTUM DOT MIXTURE, QUANTUM DOT LIGHT-EMITTING LAYER AND MANUFACTURING METHOD 京东方科技集团股份有限公司 2023-09-21 WO disclosed
US-10815268-B2 15-oxosteroid compound and process for producing the same ASKA PHARMACEUTICAL CO., LTD. (JP) 2020-10-27 US disclosed
EP-0679152-B1 ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES COSMOS PHARM CORP (US) 1997-08-27 EP disclosed
EP-0679152-A1 ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES. LAFOR LAB LTD (US) 1995-11-02 EP disclosed
WO-1994015900-A1 ANTI-ANDROGENIC CYCLO AND BICYCLO ALKENES LAFOR LABORATORIES LIMITED (US) 1994-07-21 WO disclosed
US-5264619-A Anti-androgenic cyclo and bicyclo alkenes LAFOR LABORATORIES LIMITED (US) 1993-11-23 US disclosed
EP-0364470-A1 ALICYCLIC COMPOUNDS BTG INTERNATIONAL LIMITED (GB) 1990-04-25 EP disclosed
WO-1988009786-A1 ALICYCLIC COMPOUNDS AND THEIR CONTRACEPTIVE USE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1988-12-15 WO disclosed
US-4005029-A Laundering adjunct THE PROCTER & GAMBLE COMPANY (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815268-B2 15-oxosteroid compound and process for producing the same HSD17B7, HSD11B1, HSD11B2 THRB 199/4885CYP3A4 109/4885CYP2C9 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.