Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2909930 | 0.99 | FOLH1 (0.45) | FOLH1MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL2912099 | 0.86 | LOXL2 (0.40) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| Hydrochloric Acid SCHEMBL2909153 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2NOS1HIF1A | |
| SCHEMBL5654877 | 0.80 | ALDH1A1 (0.42) | TP53 | |
| SCHEMBL2912497 | 0.74 | FOLH1 (0.41) | FOLH1TP53HTTCYP2C9HIF1A | |
| SCHEMBL27543741 | 0.72 | FOLH1 (0.58) | FOLH1MRGPRX4MEP1BRAB9ACYP2D6 | |
| SCHEMBL1310185 | 0.72 | FOLH1 (0.61) | FOLH1MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL5856499 | 0.72 | FOLH1 (0.61) | FOLH1MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL46935 | 0.71 | BCL2 (0.66) | FOLH1MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL2707508 | 0.71 | FOLH1 (0.66) | FOLH1MEP1BCYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507659-B2 | Method for chemically modifying biopolymer and polypeptide | FUJIFILM CORPORATION (JP) | 2013-08-13 | — | — | US | claimed |
| EP-2221334-B1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER AND POLYPEPTIDE | FUJIFILM CORP (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-8507659-B2 | Method for chemically modifying biopolymer and polypeptide | FUJIFILM CORPORATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20100323421-A1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER AND POLYPEPTIDE | FUJIFILM CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2221334-A1 | METHOD FOR CHEMICALLY MODIFYING BIOPOLYMER OR POLYPEPTIDE | FUJIFILM Corporation (JP) | 2010-08-25 | — | — | EP | disclosed |