Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.56 |
| ▸ | GABRP | O00591 | 1/20 | 0.56 |
| ▸ | GABRD | O14764 | 1/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595011 | 1.00 | PPARG (0.69) | PPARGKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL2874033 | 0.80 | POLH (0.79) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7072657 | 0.80 | KMT2A (0.71) | PPARGKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL3191617 | 0.78 | PPARG (0.70) | PPARGKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL21236746 | 0.77 | PPARG (0.80) | PPARGKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL29494586 | 0.77 | PPARG (0.80) | PPARGKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL4839605 | 0.76 | PLG (0.67) | PPARGKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL19236007 | 0.76 | XDH (0.72) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL27772069 | 0.74 | POLH (0.76) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| Apigenin SCHEMBL15475269 | 0.74 | CYP1B1 (0.89) | PPARGKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116942656-A | Application of naringenin derivative in preparation of anti-pancreatitis medicine | 四川大学华西医院 | 2023-10-27 | — | — | CN | disclosed |