Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.34 |
| ▸ | LIPE | Q05469 | 4/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096753 | 0.90 | F11 (0.34) | CXCR2LIPEF11F2PRSS1 | |
| SCHEMBL14934883 | 0.87 | CXCR2 (0.39) | CXCR2LIPEF11F2PRSS1 | |
| SCHEMBL29124648 | 0.84 | UCHL1 (0.34) | CXCR2F11F2PRSS1PRSS2 | |
| SCHEMBL17802731 | 0.83 | CXCR2 (0.38) | CXCR2LIPEF11F2PRSS1 | |
| SCHEMBL28903798 | 0.82 | ALDH1A1 (0.37) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17389030 | 0.79 | LIPG (0.39) | CXCR2ROCK1JAK2BTKLIPG | |
| SCHEMBL20237032 | 0.78 | JAK2 (0.37) | CXCR2ROCK1JAK2BTKLIPG | |
| SCHEMBL30615277 | 0.78 | JAK2 (0.37) | CXCR2F11ROCK1JAK2BTK | |
| SCHEMBL17951295 | 0.78 | JAK2 (0.37) | CXCR2F11ROCK1JAK2BTK | |
| SCHEMBL20237129 | 0.77 | LPL (0.33) | CXCR2JAK2BTKLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |