Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910850 | 0.92 | MAPT (0.39) | GAAMAPK1HSD17B10MAPTTRPV1 | |
| SCHEMBL2909504 | 0.84 | SYK (0.41) | GAAKMT2ASYKMEN1ALDH1A1 | |
| SCHEMBL2902816 | 0.84 | PDCD1 (0.41) | HSD17B10MAPTSYKTP53 | |
| SCHEMBL2906139 | 0.71 | KMT2A (0.41) | GAATSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL2910038 | 0.70 | SYK (0.39) | SYK | |
| SCHEMBL14095785 | 0.68 | KMT2A (0.56) | USP2TSHRPKMCCR6KMT2A | |
| SCHEMBL2906140 | 0.68 | TP53 (0.35) | GAAMAPTKMT2AMEN1TP53 | |
| SCHEMBL2909267 | 0.68 | TP53 (0.35) | GAAMAPTKMT2AMEN1TP53 | |
| SCHEMBL2901841 | 0.67 | VCP (0.43) | PKMALDH1A1 | |
| SCHEMBL2901839 | 0.67 | VCP (0.43) | PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-B1 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARM CORP (US) | 2010-08-18 | — | — | EP | claimed |